Blar i forfatter "Lutsey, Pamela L."

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    • Autoimmune disease and risk of postpartum venous thromboembolism 

      Walker, Rob F.; Zakai, Neil A.; Mason, Susan M.; MacLehose, Richard F.; Norby, Faye L.; Evensen, Line Holtet; Alonso, Alvaro; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Background - The risk of pregnancy-related mortality in the United States has nearly doubled since 1990, with venous thromboembolism (VTE) accounting for approximately 10% of these deaths.<p> <p>Objectives - The objective of this study was to assess whether preexisting autoimmune disease is a risk factor for postpartum VTE.<p> <p>Methods - Using the MarketScan Commercial and Medicare Supplemental ...

    • Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors 

      Thibord, Florian; Klarin, Derek; Brody, Jennifer A.; Chen, Ming-Huei; Levin, Michael G.; Chasman, Daniel I.; Goode, Ellen L.; Hveem, Kristian; Teder-Laving, Maris; Martinez-Perez, Angel; Aïssi, Dylan; Daian-Bacq, Delphine; Ito, Kaoru; Natarajan, Pradeep; Lutsey, Pamela L.; Nadkarni, Girish N.; de Vries, Paul S.; Cuellar-Partida, Gabriel; Wolford, Brooke N.; Pattee, Jack W.; Kooperberg, Charles; Brækkan, Sigrid Kufaas; Li-Gao, Ruifang; Saut, Noemie; Sept, Corriene; Germain, Marine; Judy, Renae L.; Wiggins, Kerri L.; Ko, Darae; O'Donnell, Christopher J.; Taylor, Kent D.; Giulianini, Franco; De Andrade, Mariza; Nøst, Therese Haugdahl; Boland, Anne; Empana, Jean-Philippe; Koyama, Satoshi; Gilliland, Thomas; Do, Ron; Huffman, Jennifer E.; Wang, Xin; Zhou, Wei; Manuel Soria, Jose; Carlos Souto, Juan; Pankratz, Nathan; Haessler, Jeffery; Hindberg, Kristian Dalsbø; Rosendaal, Frits R; Turman, Constance; Olaso, Robert; Kember, Rachel L.; Bartz, Traci M.; Lynch, Julie A.; Heckbert, Susan R.; Armasu, Sebastian M.; Brumpton, Ben Michael; Smadja, David M.; Jouven, Xavier; Komuro, Issei; Clapham, Katharine R.; Loos, Ruth J F; Willer, Cristen J.; Sabater-Lleal, Maria; Pankow, James S.; Reiner, Alexander P.; Morelli, Vania Maris; Ridker, Paul M.; Vlieg, Astrid van Hylckama; Deleuze, Jean-François; Kraft, Peter; Rader, Daniel J.; Psaty, Bruce M.; Skogholt, Anne Heidi; Emmerich, Joseph; Suchon, Pierre; Rich, Stephen S.; Vy, Ha My T; Tang, Weihong; Jackson, Rebecca D.; Hansen, John Bjarne; Morange, Pierre-Emmanuel; Kabrhel, Christopher; Trégouët, David-Alexandre; Damrauer, Scott M.; Johnson, Andrew D.; Smith, Nicholas L. (Journal article; Tidsskriftartikkel, 2022)
      <p><i>Background:</i> Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand ...

    • Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis 

      Evensen, Line Holtet; Folsom, Aaron R.; Pankow, James S.; Hansen, John-Bjarne; Allison, Matthew; Cushman, Mary; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-27)
      Background - Several hemostatic factors and inflammatory markers are associated with the risk of incident venous thromboembolism (VTE), however, most existing data are from case-control studies in Caucasian populations.<p> <p>Objectives - We aimed to prospectively confirm previous findings and explore less studied biomarkers in relation to VTE risk in a multi-racial/multi-ethnic cohort.<p> <p>Methods ...

    • Incidence and Risk Factors of Pulmonary Hypertension After Venous Thromboembolism: An Analysis of a Large Health Care Database 

      Lutsey, Pamela L.; Holtet Evensen, Line; Thenappan, Thenappan; Prins, Kurt W.; Walker, Rob F.; Farley, Joel F.; Maclehose, Richard F.; Alonso, Alvaro; Zakai, Neil A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-15)
      Background<p> <p>Pulmonary hypertension (PH) is a devastating potential complication of pulmonary embolism, a manifestation of venous thromboembolism (VTE). The incidence of and risk factors for PH in those with prior VTE are poorly characterized. <p>Methods and Results <p>International Classification of Diseases (ICD) codes from inpatient and outpatient medical claims from MarketScan administrative ...

    • Inpatient versus outpatient acute venous thromboembolism management: Trends and postacute healthcare utilization from 2011 to 2018 

      Lutsey, Pamela L.; Walker, Rob F.; Maclehose, Richard F.; Norby, Faye L.; Evensen, Line H.; Alonso, Alvaro; Zakai, Neil A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-08)
      Background - Acute outpatient management of venous thromboembolism (VTE), which includes pulmonary embolism (PE) and deep vein thrombosis (DVT), is perceived to be as safe as inpatient management in some settings. How widely this strategy is used is not well documented.<p> <p>Methods and Results - Using MarketScan administrative claims databases for years 2011 through 2018, we identified patients ...